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Risk of Hip Fracture in Community-dwelling and Institutionalized Osteoporotic Patients: A 3-year Study

O. Bruyère, M. Hiligsmann, B. Zegels, A. Neuprez, J. Reginster

2011

651 participants · 6 citations

Abstract

Summary Background and aims It has been previously suggested that the incidence of hip fracture is higher among people living in nursing homes than among community-dwelling people. However, it is not clear whether this is a consequence of nursing home residency or of the greater age of the residents. We have examined the relationship between the place of residence and hip fracture incidence, in a prospective 3-year study. Methods Women from nine countries included in this study were part of the placebo group of a randomized controlled trial having assessed the long-term effect of a new antiosteoporotic drug. All women were osteoporotic and received placebo and vitamin D during the 3 years of follow-up. All the institutionalized (nursing home, medical house) women ( n = 217) were included in this post hoc analysis and three noninstitutionalized age- and country-matched controls were included ( n = 651). Results The mean (and standard deviation) age of the patients was 80.4 (5.6) years in the institutionalized women and 80.2 (5.8) years in the noninstitutionalized women ( p = 0.87). After 3 years of follow-up, 37 fractures occurred: 12 (5.5%) in institutionalized women and 25 (3.8%) in noninstitutionalized women. The difference between the two groups was not statistically significant ( p = 0.29). After controlling for age, body mass index, femoral neck bone mineral density and prevalent nonvertebral fracture, the residence status of the patient (institutionalized vs.…

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 651 participants or records.

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