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C-reactive protein, Epstein-Barr virus, and cortisol trajectories in refugee and non-refugee youth: Links with stress, mental health, and cognitive function during a randomized controlled trial

C. Panter-Brick, K. Wiley, A. Sancilio, R. Dajani, K. Hadfield

Brain, behavior, and immunity, 2020

45 citations

Abstract

Highlights • We observed multiple CRP, EBV, and HCC trajectories, indicating within-population heterogeneity.• Refugees and non-refugee adolescents showed similar CRP and HCC trajectories.• Rising CRP levels were related to perceived stress, high HCC to insecurity.• Post-intervention, HCC reduced by more than one third, while CRP and EBV did not.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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