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Cortisol Circadian Rhythm and Sarcopenia in Patients With Type 2 Diabetes: A Cross‐Sectional Study

Fu-Peng Liu, Qing Yang, Kai Yang, Jing Sun, Yan-Ying Li, Bo Ban, Yan-Gang Wang, Mei Zhang

Journal of Cachexia, Sarcopenia and Muscle, 2025

17 citations

Abstract

Patients with Type 2 diabetes mellitus (T2DM) have elevated late‐night cortisol levels and a flattened circadian rhythm. Cortisol oversecretion mediates muscle breakdown and reduces muscle strength and mass, thus possibly leading to sarcopenia. This study first investigated the association between cortisol circadian rhythm and sarcopenia in patients with T2DM.

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