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The Relationship Between Metacognitive Beliefs and Salivary Cortisol, BDNF, and NDNF Levels: A Cross‐Sectional Study

Süheyb Okur, B. Bayraktar, Fatma Tosun Köse

Brain and Behavior, 2025

4 citations

Abstract

The main objective of this study is to non‐invasively investigate the relationship between metacognitive beliefs and cortisol, the primary stress output of the hypothalamic‐pituitary‐adrenal (HPA) axis, as well as neurotrophic factors associated with neuroplasticity brain‐derived neurotrophic factor and neuron‐derived neurotrophic factor (BDNF and NDNF). Within this framework, the hypotheses that negative metacognitions would be associated with increased cortisol and decreased BDNF levels, and that cortisol might play a mediating role in this relationship, were tested.

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