Evidence Hub

Sarcopenia and Cortisol Among Older Nursing Home Residents: A Cross-Sectional Study

Cristina Marques de Almeida Holanda, Patrícia Vidal de Negreiros Nóbrega, J. Araújo, M. Piuvezam, H. Costa, M. Moreira, Á. Maciel

2021

70 participants · 1 citation

Abstract

Background: Recent studies indicate that the prevalence of sarcopenia among older adults living in long-term care facilities may be high. The pathophysiological mechanisms of sarcopenia are complex and interdependent. The role of cortisol deserves attention as a possible modulator in the genesis of sarcopenia. The objective this study is to analyze the relationship between sarcopenia and cortisol in older nursing home residents. Method: A cross-sectional study conducted with 70 older people. Sarcopenia was assessed using the EWGSOP2 algorithm and cortisol by saliva collection. The T-test, Chi-squared test and ANOVA statistical analyzes were used (p <0.05). Results: A total of 17.1% of the older adults evaluated were considered sarcopenic. The related variables were older age (p = 0.001); lower body mass index (p = 0.008); lower measurements of brachial circumference (p <0.001), waist (p = 0.011) and hips (p = 0.001). The cortisol levels were higher among the sarcopenic older adults for the three measures throughout the day (p = 0.02), as well as for the derived measures. Conclusion: The higher salivary cortisol levels found in sarcopenic older nursing home residents help to understand the underlying mechanisms of sarcopenia and the healthcare of this public.

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 70 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free