Bone mineral denisty, 25-VIT D and parathormone hormone serum levels in males with type 2 diabetes
Abstract
Background: Vitamin D (1,25(OH)2D3) is a steroid hormone that has a range of physiological functions in skeletal and non-skeletal tissues, and can contribute to prevent and/or treat osteoporosis, obesity, and type 2 diabetes mellitus (T2DM). Vitamin D is a topic of great interest for the scientific community as well as for the layman. The commonly-know function of vitamin D has been associated with skeletal tissue, in which vitamin D influences mineralization, bone turnover rate, and occurrence of fractures, contributing to the prevention and treatment of osteoporosis. Objective: To assess vitamin D and parathyroid hormone serum levels, and correlate it with osteoporotic and fracture risk in males with type-2 diabetes. Patients and methods: This was a prospective case-control study carried out at Department of Internal Medicine, (Damietta) Faculty of Medicine, Al-Azhar University between January 2018 to January 2021. It included 70 males with type-2 diabetes mellitus, and a comparison group (control group) of 70 healthy individuals. All were submitted to full clinical assessment by history taking, clinical examinations, laboratory investigations, and DEXA scan. Vitamin and parathormone hormones were assessed and correlated with the results of DEXA scan. Results:
How strong is the evidence?
Evidence Hub reads this as a case-control, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 70 participants or records.
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