Clinico-Epidemiological Assessment of Vitamin D Deficiency in Vertebral Fragility Fracture Patients: A Descriptive Observational Study from A Tertiary Care Hospital in Northwestern India
Abstract
Background: Vitamin D deficiency is a widely prevalent nutritional disorder, particularly among the elderly, and has been implicated as a significant risk factor for osteoporotic fragility fractures. However, data regarding its prevalence specifically in patients with vertebral fragility fractures from Northwestern India remain limited. Aim: To assess the prevalence of vitamin D deficiency in patients presenting with vertebral fragility fractures at a tertiary care hospital in Northwestern India and to evaluate its correlation with demographic and fracture-related variables. Materials and Methods: This hospital-based, cross-sectional descriptive observational study was conducted at the Department of Orthopaedics, S.M.S. Medical College and Hospital, Jaipur, Rajasthan. A total of 45 patients aged >16 years with confirmed vertebral fragility fractures were enrolled after obtaining informed consent. Serum 25-hydroxyvitamin D [25(OH)D] levels were measured using chemiluminescent immunoassay (CLIA). Vitamin D status was categorized as deficient (<20 ng/mL), insufficient (20–29 ng/mL), or sufficient (≥30 ng/mL). Demographic data, fracture type (wedge, biconcave, crush), fracture site, and number of fractures were recorded. Data were analyzed using descriptive statistics. Results: Of the 45 patients, 26 (57.8%) were female and 19 (42.2%) were male with a mean age of 62.8 ± 6.4 years. The mean serum 25(OH)D level was 19.22 ± 3.95 ng/mL. All 45 patients (100%) had suboptimal vitamin…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 45 participants or records.
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