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Functional Outcome of ORIF of Clavicle Fracture with Clavicular Plate and Screw

Md. Jonaed Hossain, Mohammad Zakaria Hemal, Md. Zahidur Rahman, Md. Harunur Rashid, S. Rahim, M. M. Al Hasan, S. Sarwar

Scholars Journal of Applied Medical Sciences, 2025

Abstract

Background: Chronic Kidney Disease (CKD) is a progressive condition that significantly affects the global population, with increasing prevalence in low- and middle-income countries like Bangladesh. Among CKD patients, cardiovascular disease remains a leading cause of morbidity and mortality, with arterial stiffness emerging as a critical indicator of cardiovascular risk. The brachial-ankle pulse wave velocity (baPWV) is a non-invasive measure of arterial stiffness, offering valuable insights into vascular health. This study explores the association between baPWV and clinical parameters in non-dialysis CKD patients in Bangladesh. Objective: To investigate the association between baPWV and various clinical and laboratory parameters in non-dialysis CKD patients in Bangladesh. Methods: A cross-sectional observational study was conducted at the Department of Nephrology, Dhaka Medical College, between September 2021 and March 2023. The study involved 100 non-dialysis CKD patients (50 with vitamin D deficiency and 50 without), aged 18 years or older, in stages 3-5. Demographic, clinical, and laboratory data were collected, and baPWV was measured. Data analysis was performed using SPSS version 26.0 with statistical tests including t-tests, ANOVA, and regression analysis. Results: Vitamin D deficiency was associated with higher baPWV compared to non-deficient patients, with significant differences observed across all CKD stages (p<0.05). The mean baPWV in the vitamin D deficient…

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Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.

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