Surgical Treatment of Tibial Tubercle Fractures in Osteogenesis Imperfecta: A Restrospective Case Series
Abstract
Background: Osteogenesis imperfecta (OI) is a rare bone fragility disorder involving type I collagen. Although fragility fractures are common, tibial tubercle apophyseal fracture reporting is limited. This study evaluates our series of tibial tubercle operative fractures in OI patients.
Methods: Retrospective review of all operative tibial tubercle fractures from 2010 to 2022, at a level one pediatric trauma and osteogenesis imperfecta referral center identified four patients with concomitant OI. Demographic information, OI type, antecedent and subsequent fracture history, surgical treatment, and OI treatment method were collected. Comparison was made with non-OI operatively treated tibial tubercle patients (n = 183).
Results: The mean OI tibial tubercle surgical patient was 11 years (range 9-14). The mean non-OI tibial tubercle surgical patient was 14.5 years (range 8.5-17.0). Two out of four OI patients were female (50%) and 94.5% were male in the non-OI group. Within the OI group, one patient was diagnosed with OI after their tibial tubercle fracture (15 months later). OI types included: type I (n = 3) and type IV (n = 1). Before the tibial tubercle fracture, no patients were on bisphosphonate therapy and three were on vitamin D supplementation. All OI patients underwent open reduction with cannulated screw fixation. In two out of four (50%) OI patients, suture anchors were used. In the non-OI group 13.7% of patients were treated with suture anchors. Three OI patients…
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 183 participants or records.
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