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Retrieval Strategies for Embolized Left Atrial Appendage Closure Devices

Sadiq U, Ali M, Damito S, Ambrosino M, Sabri MS, Sadiq MA, Sadiq MH, Kovach R et al.

JACC. Case reports, 2026

Abstract

Background: Device embolization (DE) is a rare but potentially life-threatening complication of left atrial appendage occlusion (LAAO). As landmark trials broaden the eligible population for LAAO, operator preparedness for DE management becomes increasingly critical.

Case summary: We present 4 cases of LAAO DE managed with distinct retrieval strategies: 1) open surgical retrieval with concurrent AtriClip ligation for an endothelialized left atrial device; 2) sequential transseptal then retrograde arterial snaring for intraprocedural migration to the abdominal aorta; 3) transseptal retrieval using a dedicated ONO system with cerebral embolic protection for partial left atrial dislodgment; and 4) retrograde large-bore arterial retrieval for delayed aortic embolization.

Conclusions: Percutaneous retrieval is feasible in most cases when tailored to embolization location. Surgical backup remains indispensable. Prevention requires rigorous preprocedural imaging, accurate sizing, and routine postimplant surveillance.

Take home message: LAAO embolization has high mortality, accurate device sizing as well as follow up imaging in paramount.

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