Complete neurological recovery of spinal tuberculosis after spinal surgery and vitamin D supplementary: A case series
Abstract
Introduction and importance Deaths from tuberculosis (TB) in Indonesia are nearly 200,000 per year and higher than those from COVID-19. The problems associated with spinal TB are vitamin D deficiency, neurological deficit, disruption of daily living activities and long-term anti-TB treatment (24 months). Vitamin D acts as an anti-inflammatory, maintains vascular health, and increases calcium levels. Case presentation We reported 130 cases series spinal TB, neurological problems, vitamin D deficiencies; after surgery, anti-TB drugs and vitamin D adjuvant for 12 months. A TB diagnosis was confirmed by radiology, microbial and histopathology investigations. Clinical discussion After the treatment is shorter than standard conventional, patients had 100 % normal motor function, 3 % stiffness, 97.4 % fusion rate, 98.5 % normal vitamin D, minimal disability based on Oswestry Disability Index (ODI) scores, and normal function based on Japanese Orthopaedic Association (JOA) scores. Conclusion Vitamin D should be considered an adjuvant in spinal TB treatment, although further research is still needed to determine its efficacy and safety. Surgery and the administration of anti-TB drugs are still the standard procedures.
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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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