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Bilateral Basal Ganglia Calcification (Fahr's Syndrome) Secondary to Hypoparathyroidism: A Case Series

Ali Gohar, Moeez Ahmad Saeed, Arham Saif, Azka Irfan, Humza Tariq, Ruman Shahzad, Amna Suhail, Haseeb Ahmad et al.

Clinical Case Reports, 2026

Abstract

Three cases of Fahr's syndrome presented with seizures and extrapyramidal features, all linked to hypoparathyroidism with disrupted calcium‐phosphate levels. CT confirmed basal ganglia calcification. Anticonvulsants, calcium, and vitamin D controlled seizures. Identifying metabolic triggers early—and involving neurology, endocrinology, and psychiatry—changes outcomes.

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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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