Evidence Hub

Posterior Lumbar Arthrodesis Using a Stand-Alone Hydrophilic Synthetic Bone Graft in the Setting of Postoperative Osteomyelitis/Discitis: A Case Report

Smith M

Cureus, 2026

Abstract

This single-patient case report describes an all-posterior salvage reconstruction of multilevel lumbar osteomyelitis using a stand-alone hydrophilic synthetic bone graft (HPSBG; OsteoFlo® HydroFiber™, SurGenTec, LLC, Boca Raton, FL) packed transpedicularly as the sole intervertebral graft material. Postoperative osteomyelitis with progressive vertebral body destruction commonly involves combined anterior-posterior reconstruction with corpectomy and structural cage placement, which is technically demanding and morbid in patients with poor bone quality and adjacent prior fractures. Hydrophilic synthetic bone grafts engineered to support fusion in compromised environments may permit less invasive salvage strategies. A 59-year-old woman with persistent L1-L2 osteomyelitis after a prior L2-L5 fusion for an L3 burst fracture, complicated by osteoporosis and low vitamin D levels (25-hydroxyvitamin D 15.6 ng/mL), underwent posterior-only salvage reconstruction. Through an all-posterior approach, transpedicular partial corpectomies of L1 and L2 were performed through the existing erosive defects. Intraoperative cultures grew Pseudomonas aeruginosa. The void was packed with HPSBG as the sole intervertebral graft material, with no anterior cage. Long-segment T10-pelvis fixation with a quad-rod construct provided posterior stabilisation. Computed tomography (CT) at eight months postoperatively demonstrated bridging bone through the L1-L2 defect, consistent with early anterior column…

How strong is the evidence?

Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free