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Hyperparathyroidism-Jaw Tumor Syndrome: A Rare Case

Gupta K, Asirvatham AR, Mahadevan S, Sundaram S, Kumar D, Cunnigaiper N

Cureus, 2026

Abstract

Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is an uncommon autosomal dominant disorder associated with primary hyperparathyroidism due to parathyroid adenomas and ossifying jaw tumors. We present the case of a 31-year-old male who was incidentally diagnosed with severe parathyroid hormone-dependent hypercalcemia following a traumatic upper limb fracture. Subsequent evaluation confirmed the diagnosis of HPT-JT syndrome. Early recognition, prompt surgical management, and genetic confirmation are essential to ensure appropriate treatment and prevent long-term complications.

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