Single-access mini-PCNL with flexible cystoscopy vs. multi-access mini-PCNL for complex renal stones in prospective study
Abstract
To observe the efficacy and safety of single-access minimally invasive percutaneous nephrolithotomy (MPCNL) combined with flexible cystoscopy and multi-access MPCNL in patients with complex renal stones (CRS). A total of 195 patients with CRS were prospectively randomized into two groups. Ninety-eight in the single-access MPCNL group and 97 cases as control in the multi-access MPCNL group. The stone-free rates (SFRs) at different times were considered as the primary outcome of the study. The secondary end points were operative time, hemoglobin decrease, postoperative hospital stay and operation-related complications. There was no obvious difference between two groups in patients' demographics and preoperative clinical characteristics (All P > 0.05). Postoperative data showed that mean decrease in hemoglobin level was less in single-access MPCNL group than that in multi-access MPCNL group (P < 0.001). Postoperative hospital stay in single-access MPCNL group was more shorten than that in multi-access MPCNL group (P < 0.001). Moreover, the SFRs of the postoperative 2nd day and 4th week in single-access MPCNL group were both significantly higher than those in multi-access MPCNL group (Both P < 0.05). However, in terms of the rates of low back pain, perirenal hematoma and renal artery embolization, multi-access MPCNL group were all significantly higher than single-access MPCNL group (All P < 0.05). Our study shows that single-access MPCNL and flexible cystoscopy are ideal…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 195 participants or records.
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