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Plant-Based Drinks as an Alternative to Cow's Milk in Early Life: Health Effects in Infancy, Childhood, and Adolescence

Schlune A, Nebelung N, Schidelko LP, Brettschneider AK, Dauner D, Ensenauer R

Deutsches Arzteblatt international, 2026

Abstract

Background: Plant-based milk alternatives (PBMA) are increasingly being consumed as a supplement to or replacement for cow's milk, even in infancy and childhood. Their effects on later health and growth have been insufficiently studied. We analyze the available evidence concerning the effects of PBMA consumption on health and growth in infants, children, and adolescents.

Methods: This review is based on publications retrieved by a structured literature search on health and growth outcomes of PBMA consumption in infancy, childhood, and adolescence.

Results: Comparative cross-sectional and cohort studies have shown that the intake of nutrients typically found in cow's milk, such as iodine, is lower with exclusive consumption of PBMA. Even the partial replacement of cow's milk by PBMA is associated with reduced linear growth and a lower body-mass index (BMI). The height-for-age z-score was -0.04 [-0.07; -0.01] and the BMI-for-age z-score was -0.06 [-0.09; -0.03] for each cup of PBMA in five-year-olds, corresponding to reductions of 0.2 cm in height and 0.1 kg in weight. There have been case reports of severe malnutrition and undernutrition from the exclusive or predominant consumption of PBMA, mainly in the first two years of life, but the informational value of these reports is limited. Our search did not retrieve any longitudinal studies on long-term outcomes or any randomized intervention trials comparing the consumption of cow's milk and PBMA.

Conclusion: High PBMA…

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