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Bone Health Assessment and Management among Survivors of Non-metastatic Breast Cancer: A Narrative Review

John R, Cherian KE, Sebastian P, Balakrishnan R, Backianathan S, Paul TV

Indian journal of endocrinology and metabolism, 2025

Abstract

Breast cancer, the most common hormone responsive cancer, is on a rise both globally and in India. With increased longevity of breast cancer survivors, addressing long-term complications such as osteoporosis is crucial. Several mechanisms contribute to the bone loss seen in breast cancer patients, including age, post-menopausal status, chemotherapy, and other adjuvant therapies received. Appropriate evaluation and counselling on the risks of therapy with aromatase inhibitors on bone health are much needed. Timely initiation of anti-resorptive medication can help improve bone mass, reduce the incidence of fractures, and improve quality of life.

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