Vitamin D and VDR in cancer cachexia and muscle regeneration
Abstract
// Andrea Camperi 1, 5, * , Fabrizio Pin 1, 2, * , Domiziana Costamagna 1, 2, 8 , Fabio Penna 1, 2 , Maria Lopez Menduina 1, 3 , Zaira Aversa 4 , Teresa Zimmers 5 , Roberto Verzaro 6 , Raffaella Fittipaldi 7 , Giuseppina Caretti 7 , Francesco Maria Baccino 1 , Maurizio Muscaritoli 4 , Paola Costelli 1, 2 1 Department of Clinical and Biological Sciences, University of Turin, Turin, Italy 2 Interuniversity Institute of Myology, Italy 3 Department of Physiology, Complutense University of Madrid, Madrid, Spain 4 Department of Clinical Medicine, Sapienza University of Rome, Rome, Italy 5 Indiana University School of Medicine - IUPUI, Indianapolis, IN, USA 6 Department of Surgery, M.G. Vannini Hospital, Rome, Italy 7 Department of Biosciences, University of Milan, Milan, Italy 8 Current address: Translational Cardiomyology Laboratory, Stem Cell Biology and Embryology, Department of Development and Regeneration, University Hospital Gasthuisberg, Leuven, Belgium * Andrea Camperi and Fabrizio Pin equally contributed to the present study Correspondence to: Paola Costelli, email: [email protected] Keywords: muscle wasting, regeneration, vitamin D receptor, myogenin, circulating vitamin D Received: July 28, 2016 Accepted: January 27, 2017 Published: February 21, 2017 ABSTRACT Low circulating levels of vitamin D were associated with decreased muscle strength and physical performance. Along this line, the present study was aimed to investigate: i) the therapeutic potential of…
Read the paper
Related studies
- Effectiveness of Bisphosphonates and Denosumab on Risk of Vertebral Fractures in Prostate Cancer Patients Under Androgen Deprivation Therapies: A Real-World Prospective Study
- Osteoporosis-related fractures after spinal cord injury: a retrospective study from Brazil
- Serum 25-hydroxyvitamin D, parathyroid hormone, and mortality in older men
- Lack of Association between Vitamin D Insufficiency and Cardiovascular or Fracture Risk: A UK Biobank Study
- Muscle strength and body composition are clinical indicators of osteoporosis
- Incidence of bone protection and associated fragility injuries in patients with proximal femur fractures
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.