Evidence Hub

Quantitative analysis of the effect of ICL orientation on postoperative vault: a self-controlled retrospective study

Zhu QJ, Xing XY, Chen XQ, Ma L, Yuan Y

BMC ophthalmology, 2026

2,042 participants · 1 citation

Abstract

BACKGROUND: To investigate the effect of ICL implantation orientation on the postoperative vault quantitatively. METHODS: A total of 3510 eyes from 2042 subjects who underwent ICL implantation between July 1, 2020, and June 30, 2023, were included in this self-controlled retrospective study. We selected all subjects with nonhorizontal placement in the second surgical eye and divided them into four groups: same-sized vertical placement (group A), larger-sized vertical placement (group B), same-sized oblique placement (group C), and larger-sized oblique placement (group D). The achieved and predicted vaults were compared in each group. RESULTS: A total of 126, 81, 82 and 11 subjects were included in groups A, B, C and D, respectively. The mean difference in vault between fellow eyes in groups A, B, C and D was − 284.79 ± 169.92 μm, 53.59 ± 136.06 μm, -107.30 ± 136.09 μm and 208.18 ± 118.64 μm, respectively, and all the differences were statistically significant (P < 0.001, P = 0.001, P < 0.001, P < 0.001). The mean differences between the achieved and predicted vaults of the horizontal-placement eyes in groups A, B, C and D were 23.14 ± 233.20 μm, -46.39 ± 189.22 μm, 9.45 ± 187.43 μm, and − 76.72 ± 165.68 μm, respectively, and for the nonhorizontal-placement eyes, the achieved vault of subjects in groups A, B, C and D were 294.59 ± 181.72 μm, 313.22 ± 226.52 μm, 110.02 ± 177.67 μm and 191.63 ± 257.78 μm lower than the predicted vault; all the differences were statistically…

How strong is the evidence?

Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 2,042 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free