Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism
Abstract
The overall objectives of the proposed study are to examine the consequences of chronic circadian disruption and chronic sleep restriction on metabolic function in healthy adults.
Conditions: Aging, Sleep Restriction, Circadian Disruption.
Primary outcome: Change in insulin sensitivity; Changes in glucose levels after standardized meal; Change in insulin levels after standardized meal; Change in 24h profiles of leptin; Change in 24h profiles of cortisol.
Enrollment: 21 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 21 participants or records.
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