Mechanism Underlying the Effects of Blue Light in Humans
Abstract
This study will determine which color of light is most effective in stimulating a range of biological functions in humans including activation of sleep-wake regulatory system (alertness, performance, microsleeps, brain activity), activation of the nervous system (heart rate, temperature, blood pressure, breathing rate), and shifting the timing of the internal 24-hour (circadian) pacemaker.
Conditions: Healthy, Circadian Rhythm.
Primary outcome: Subjective alertness prior to, during and after light exposure; Auditory psychomotor performance prior to, during and after light exposure; EEG power frequency prior to, during and after light exposure; Plasma melatonin and cortisol prior to, during and after light exposure; Heart rate, blood pressure, respiration rate and temperature prior to, during and after light exposure; Urinary catecholamines prior to, during and after light exposure.
Enrollment: 47 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 47 participants or records.
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