Evidence Hub

Effect of Melatonin on Postoperative Pain After Simple Nephrectomy: A Randomized Double-Blinded Controlled Study

ClinicalTrials.gov · COMPLETED, 2025

40 participants

Abstract

The aim of the study is to evaluate the role of melatonin in the management of postoperative pain in patients undergoing simple nephrectomy regarding:

* Pain score (VAS).

* Total Morphine consumption is 1st 24 hr.

* Time to the 1st rescue analgesia.

* Intra-operative and post-operative hemodynamics.

* Anxiety.

* Patient satisfaction.

* Adverse events.

Conditions: Pain Score (VAS) at 24 h Postoperatively.

Primary outcome: Pain score (VAS) at 24 h postoperatively.

Enrollment: 40 participants.

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 40 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free