ĐẶC điểm VÀ KẾT QUẢ điều TRỊ viêm phổi bệnh viện DO acinetobacter baumannii TẠI khoa NỘI HÔ HẤP bệnh viện thống nhất
Abstract
This study aimed to characterize the clinical and paraclinical features, treatment outcomes, and antibiotic resistance patterns of Acinetobacter baumannii-associated hospital-acquired pneumonia (HAP) in elderly patients. A cross-sectional descriptive study was carried out on 75 hospitalized patients aged 60 years and above who were diagnosed with A. baumannii-related HAP. The study took place at the Department of Respiratory Medicine, Thong Nhat Hospital, from April 2024 to April 2025. The majority of patients exhibited clinical manifestations including fever, productive cough, dyspnea, auscultatory crackles, leukocytosis, elevated C-reactive protein (CRP) levels, and chest radiographs revealing infiltrates in over 70% of cases. Altered mental status was notably prevalent among elderly patients, affecting 65.3%. The most frequently utilized empirical antibiotic regimens were ceftazidime plus gentamicin, piperacillin/tazobactam plus levofloxacin, and ceftazidime pus ciprofloxacin; however, only 21.3% of these empirical therapies aligned with antibiotic susceptibility testing results. Multidrug-resistant A. baumannii accounted for 84% of isolates, with 21.3% classified as multidrug-resistant (MDR), 50.7% as extensively drug-resistant (XDR), and 13.3% as pandrug-resistant (PDR). Resistance rates to β-lactam/β-lactamase inhibitor combinations and cephalosporins exceeded 85%, resistance to quinolones and aminoglycosides ranged between 60–70%, and carbapenem resistance was…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 75 participants or records.
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