The study on the prevalence and some factors related to antibiotic resistance of propionibacterium acnes at CAN THO hospital of dermato-venereology
Abstract
Background: Acne is an inflammatory disease of the hair follicles. There are many treatments from medication to non-medication in which antibiotics are a widely used and effective group. However, the recent overuse of antibiotics has led to an increase in resistance to drugs by P. acnes. Therefore, this study is extremely necessary. Objectives: To determine the antibiotic resistance rate and a number of factors related to Propionibacterium acnes antibiotic resistance rate in acne patients at Can Tho Hospital of Dermato-Venereology. Materials and methods: the cross-sectional descriptive study was carried out on of 43 acne patients at Can Tho Hospital of Dermato-Venereology. Results: resistance rates for antibiotics were cefuroxime (91.7%), ceftriaxone (87.5%), cefotaxime (87.5%), trimethoprim (85.4%), clindamycin (66.7%), ofloxacin (41.7%), ciprofloxacin (25%), levofloxacin (20.8%), tetracycline (16.7%). All patients participating in the study were resistant to at least 2 or more antibiotics of which the highest resistance level was 6 antibiotics (37.5%). Some related factors such as the history of antibiotic treatment accounted for 35.4%. Severity levels were classified into mild acne 60.1%, average 27.1% and severity 12.5%; there were two clinical forms in our study including acne vulgaris (77.1%) and cystic acne (22.9%). However, when examining the relationship between these factors and antibiotic resistance, this difference is not statistically significant. Conclusion: P.…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 43 participants or records.
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