Performance of next-generation sequencing technologies for detecting drug-resistant tuberculosis in people with pulmonary tuberculosis
Abstract
Objectives: This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows: To determine the diagnostic accuracy of next-generation sequencing (NGS) technologies, specifically targeted NGS (tNGS) and whole-genome sequencing (WGS), for detecting drug-resistant tuberculosis among people with pulmonary tuberculosis, using phenotypic drug susceptibility testing as the primary reference standard.
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