Effects of quercetin ingestion on neuromuscular system following single session of resistance exercise at differing intensities in older adults
Abstract
The purpose of this study was to investigate whether quercetin ingestion increases the decline in muscle contractile capacity due to a single resistance exercise session at differing intensities. Thirty-eight older adults took part in this study. They were divided into three intensity groups: low- (LI), moderate- (MI), and high-intensity (HI) groups. Each participant completed two single resistance exercise sessions of resistance exercise at 40 (LI), 60 (MI), or 80 (HI) percent of maximal voluntary contraction. Before each session, they ingested either a placebo or quercetin glycoside (500 mg). Motor unit behavior and electrically elicited contraction torque were measured by high-density electromyography and neuromuscular electrical stimulation at pre-ingestion, post-ingestion, and post-exercise. Quercetin ingestion decreased the motor unit recruitment thresholds from pre- to post-ingestion (p < 0.001). The decline in electrically elicited contraction torque following exercise was greater with quercetin than placebo ingestion in LI and MI groups (low: p = 0.014; moderate: p = 0.025), but not in the HI group (p = 0.792). The greater the decline of electrically elicited contraction torque following exercise by quercetin ingestion, the greater the decrease in the recruitment threshold of motor units with a higher threshold by quercetin ingestion in LI and MI groups (low: p = 0.047, rs = 0.566; moderate: p = 0.011, rs = 0.692), but not in the HI group (p = 0.228). These results…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.
Read the paper
Related studies
- Quercetin Influences Quorum Sensing in Food Borne Bacteria: In-Vitro and In-Silico Evidence
- Phenolic-protein interactions: insight from in-silico analyses – a review
- In Silico Discovery of Candidate Drugs against Covid-19
- Neuropharmacological Effects of Quercetin: A Literature-Based Review
- In vitro and in silico anti-dengue activity of compounds obtained from Psidium guajava through bioprospecting
- Effect of Quercetin Rich Onion Extracts on Bacterial Quorum Sensing
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.