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Effects of Withania somnifera in patients of schizophrenia: A randomized, double blind, placebo controlled pilot trial study

Akshay P. Agnihotri, S. Sontakke, V. Thawani, A. Saoji, V. S. Goswami

Indian Journal of Pharmacology, 2013

40 citations

Abstract

417 Indian Journal of Pharmacology | August 2013 | Vol 45 | Issue 4 4. Hayes NA, Foreman JC. The activity of compounds extracted from feverfew on histamine release from rat mast cells. J Pharm Pharmacol 1987;39:466-70. 5. Kandaswami C, Middleton E. Free radical scavenging and antioxidant activity of plant flavonoids. Adv Exp Med Biol 1994;366:351-76. 6. Middleton E, Kandaswami C, Theoharides TC. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol Rev 2000;52:673-751. 7. Rotelli AE, Guardia T, Juárez AO, de la Rocha NE, Pelzer LE. Comparative study of flavonoids in experimental models of inflammation. Pharmacol Res 2003;48:601-6. 8. Deschner EE, Ruperto J, Wong G, Newmark HL. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis 1991;12:1193-6. 9. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54. 10. Yadav P, Ganeshpurkar A, Rai G. In vitro H+ -K+ ATPase inhibitory potential of methanolic extract of Cissus quadrangularis Linn. Pharmacogn Res 2012;4:123-6.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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