Evidence Hub

Cardio-metabolic benefits of quercetin in elderly patients with metabolic syndrome

V. Shatylo, I. Antoniuk-Shcheglova, S. Naskalova, O. Bondarenko, Anna Havalko, Dmytro Krasnienkov, O. Zabuga, V. Kukharskyy et al.

PharmaNutrition, 2021

25 citations

Abstract

Abstract Background Quercetin is regarded as a promising phytochemical in treating metabolic syndrome (MetS). Methods Present study is a randomized, placebo-controlled, double-blind clinical trial aimed at evaluating effects of quercetin on different aspects of MetS in patients aged 60 + . Study participants consumed two quercetin-containing or placebo tablets 3 times per day (daily dose = 240 mg) during 3 months. Results Quercetin administration decreased body weight (−0.32 kg; p = 0.007) and body mass index (−0.12 kg/m2; p = 0.01). The blood pressure was also decreased: systolic blood pressure: −7.7 mm Hg (p Conclusion These findings indicate that quercetin may be effective in treating MetS. This trial was registered by Ukrainian Registry of Clinical Trials on October 30, 2017 (registration №1339).

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free