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Quercetin as a Nutritional Intervention: Enhancing Growth, Metabolism, and Immune Gene Modulation in Labeo rohita

Dar SA, Kumar S, Saini VP, Abhiman, Rani S, Iqbal G, Swain S, Kumar R et al.

ACS omega, 2025

Abstract

The objective of the study was to evaluate the use of quercetin-supplemented diet as a growth, metabolism, and immunity promoter in Labeo rohita. Fish (8 ± 0.5 g) were randomly divided into five groups in triplicates (30 fish in each replicate) in circular tanks of 2000 L capacity. The fish were fed on a control diet (0% quercetin and four experimental diets supplemented with quercetin inclusion levels 0.2% (T1), 0.4% (T2), 0.8% (T3), and 1.6% (T4)). After the experimental period, the highest growth performance weight gain %, specific growth rate, protein energy ratio, and intestinal somatic index were recorded in the T4 group, followed by the T3 group. The lowest yield was recorded in the control group. However, the feed conversion ratio was significantly decreased with the 1.6 quercetin-supplemented group. The activity of digestive and metabolic enzymes of quercetin-fed groups was significantly different (p p p p Aeromonas hydrophila. Consequently, quercetin supplementation is recommended at a level of 1.6% to improve the growth performance, antioxidative capacity, and immune response of L. rohita.

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