Diesel Siphoner's Lung: Acute exogenous lipoid pneumonia following accidental aspiration of diesel fuel-two case reports and a literature review
Abstract
Background: Diesel Siphoner's Lung is a severe, life-threatening subtype of acute exogenous lipoid pneumonia (ELP) caused by accidental diesel fuel aspiration. While diagnosis is typically straightforward with a clear exposure history, clinical management is challenging due to rapidly progressive respiratory failure. Given the relative rarity of such accidents and the lack of standardized management guidelines, optimizing therapeutic strategies remains a significant clinical challenge.
Case presentation: We report two cases of acute ELP resulting from diesel siphoning-a distinct clinical entity termed 'Diesel Siphoner's Lung'-demonstrating highly divergent clinical trajectories. Case 1, a previously healthy 48-year-old male, presented with acute lung injury (ALI) 8 hours post-aspiration. Prompt interventions, including endotracheal intubation, serial segmental bronchoalveolar lavage (sBAL) and systemic corticosteroid therapy, were adopted. Following progressive clinical improvement, the patient was extubated on the 8th day and subsequently discharged on the 25th day with substantial radiological resolution. Conversely, Case 2-a 45-year-old male with a history of diabetes and hypertension-was admitted with established acute respiratory distress syndrome (ARDS) 2 days post-aspiration. His clinical course was severely complicated by multidrug-resistant nosocomial infections and a left-sided hydropneumothorax, refractory to similar clinical management with endotracheal…
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Severe clinical outcomes of COVID-19 associated with proton pump inhibitors: a nationwide cohort study with propensity score matching
- Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors
- Inhalable Mannosylated Rifampicin–Curcumin Co-Loaded Nanomicelles with Enhanced In Vitro Antimicrobial Efficacy for an Optimized Pulmonary Tuberculosis Therapy
- Association between cord blood 25-hydroxyvitamin D concentrations and respiratory tract infections in the first 6 months of age in a Korean population: a birth cohort study (COCOA)
- GC-MS Analysis and Biomedical Therapy of Oil from n-Hexane Fraction of Scutellaria edelbergii Rech. f.: In Vitro, In Vivo, and In Silico Approach
- Novel Pharmacokinetic/Pharmacodynamic Parameters Quantify the Exposure–Effect Relationship of Levofloxacin against Fluoroquinolone-Resistant Escherichia coli
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.