EuSHT Acts as a Hub Gene Involved in the Biosynthesis of 6-Hydroxyluteolin and Quercetin Induced by Salt Stress in Eucommia ulmoides
Abstract
Salt stress inhibits plant growth and affects the biosynthesis of its secondary metabolites. Flavonoids are natural compounds that possess many important biological activities, playing a signi fi cant role in the medicinal activity of Eucommia ulmoides ( E. ulmoides ). To investigate the mechanism by which salt stress affects the biosynthesis of fl avonoids in E. ulmoides , a comprehensive analysis of metabolomics and transcriptomics was conducted. The results indicated that salt stress led to the wilting and darkening of E. ulmoides leaves, accompanied by a decrease in chlorophyll levels, and signi fi cantly induced malondialdehyde (MDA) and relative electrical conductivity. During salt stress, most metabolites in the fl avonoid biosynthesis pathway of E. ulmoides were upregulated, indicating that fl avonoid biosynthesis is likely the main induced pathway under salt stress. Among them, secondary metabolites such as 6-Hydroxyluteolin and Quercetin are likely key metabolites induced by salt stress. The correlation analysis of transcriptomics and metabolomics revealed that EuSHT is a hub gene induced by salt stress, promoting the production of fl avonoids such as 6-Hydroxyluteolin. The co-expression network showed a strong positive correlation between EuSHT and the biosynthesis of 6-Hydroxyluteolin and Quercetin, while it exhibited a negative correlation with Catechin biosynthesis. The branches leading to Luteolin and Dihydroquercetin are likely the main pathways for fl avonoid…
Read the paper
Related studies
- Quercetin Influences Quorum Sensing in Food Borne Bacteria: In-Vitro and In-Silico Evidence
- Phenolic-protein interactions: insight from in-silico analyses – a review
- In Silico Discovery of Candidate Drugs against Covid-19
- Neuropharmacological Effects of Quercetin: A Literature-Based Review
- In vitro and in silico anti-dengue activity of compounds obtained from Psidium guajava through bioprospecting
- Effect of Quercetin Rich Onion Extracts on Bacterial Quorum Sensing
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.