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PO-90 | CAPSULASE® (PEA (palmitoylethanolamide), PHYTOSOME (quercetin from Sophora japonica L. 40% soy lecithin, microcrystalline cellulose, aerosil), CASPEROME (Boswellia serrata R., gum resin 40%, soy lecithin, microcrystalline cellulose, aerosil), bromelain 2,

Società Italiana per lo studio delle Cefalee (SISC)

Confinia cephalalgica (Milano), 2025

Abstract

Background: Craniofacial pain is mediated for a large part of the territory by the trigeminocervical complex. The nasal and oral mucosa, the tongue and the teeth are structures that can be the cause of facial pain, as can dental treatments (such as avulsions) that lead to the establishment of so-called “atypical” facial pain conditions. The IHS classification establishes the diagnostic criteria in chapter 13 dedicated to Cranial neuralgia and facial pain of central origin.

Methods: We report the case of a 67-year-old female patient with orofacial pain and right hemifacial edema following avulsion of the upper right premolar arch due to the presence of a granuloma associated with the placement of synthetic bovine bone in the right maxillary area for maxillary sinus elevation. The patient was treated with antibiotic therapy for 7 days starting from the day before the surgery and therapy with Capsulase 1+1 cp/day was introduced to contain the edema and orofacial pain with neuralgic notes at the level of the I and II branch of the right trigeminal nerve. The patient filled out a diary on clinical evolution and especially pain monitoring using the VAS (Visual Analogue Scale). Data on efficacy and tolerability were also collected.

Results: The patient reported a reduction in edema after 7 days with elimination of the same after 14 days of administration of Capsulase 1+1 cp/day. The intensity of pain in the first 14 days was significantly reduced (VAS: 9 at T0; VAS: 2 at T1 – 14…

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