Study on Protection Function of Quercetin on Ischemia-reperfusion Injury of Liver and its Mechanism
Abstract
Objective: To report quercetin protection against hepatic ischemia-reperfusion injury and its mechanism were reviewed. Methods: The correlative literature retrieval in recent years, the quercetin on the protective effects of liver ischemia-reperfusion injury in experimental and clinical research in the case of analysis and summary. Results: The effect of quercetin is widespread, but by anti oxygen free radical and lipid peroxidation, inhibiting mitochondrial damage, intracellular calcium overload and cell apoptosis, improving microcirculation after reperfusion and anticoagulant mechanism of protecting ischemia-reperfusion injury of the liver. Conclusion: The quercetin has protective effect to liver ischemia-reperfusion injury, research and application value.
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