Detection of an O1 Vibrio cholerae Strain in the Blood of a Patient with Acute Cholangitis: A Rare Case Report
Abstract
Acute cholangitis is a potentially life-threatening condition commonly caused by bacterial infections of the biliary tract. Here, we present an unusual case of acute cholangitis caused by Vibrio cholerae in a 76-year-old man with a history of hypertension, diabetes, asthma, and post-cholecystectomy who presented with upper abdominal pain, jaundice, and fatigue. Lab results showed elevated inflammatory markers and bilirubin. Imaging revealed gallstones and bile duct dilation. Blood cultures isolated non-toxigenic Vibrio cholerae, which was highly susceptible to all tested antibiotics. The patient was successfully treated with piperacillin/tazobactam and levofloxacin, along with supportive care. His symptoms resolved, and subsequent cultures were negative. This case highlights a rare instance of non-cholera Vibrio cholerae causing acute cholangitis and bacteremia in an elderly patient.
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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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