Three new flavonoids from the active extract of Fallopia convolvulus
Abstract
Five solvent extracts (ethanol, petroleum ether, EtOAC, n-butanol, and water) from Fallopia convolvulus (L.) Love were separated and their inhibitory effects on nitric oxide production in lipopolysaccharide-activated macrophages were evaluated. Three new flavonoids, falloconvolin A (1), falloconvolin B (2), and quercetin-3-O-(2-E-sinapoxyl)-glucopyranoside (3), together with 17 known phenolic compounds, were isolated from the active EtOAC extract, and their structures were elucidated on the basis of spectroscopic analysis and literature data.
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