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Brevibacterium casei catheter-related bloodstream infection in an immunocompromised patient with multiorgan failure in Dubai hospital, UAE.

Nabi A, Lone R, Alatoom A, Habous M, Mathur B, Monga R

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2026

Abstract

Brevibacterium casei, historically regarded as a harmless skin commensal, is increasingly recognized as an opportunistic pathogen in immunocompromised individuals. Catheter-Related Bloodstream Infections (CRBSIs) due to B. casei remain rare but are clinically significant, particularly among patients with multiple comorbidities and indwelling vascular devices. We report a CRBSI caused by B. casei in a 69-year-old male with ischemic heart disease, chronic obstructive pulmonary disease and acute kidney injury. The diagnosis was established through blood cultures from both a dialysis catheter and a peripheral vein. The patient showed clinical improvement following catheter removal and a combination of Piperacillin-Tazobactam with Levofloxacin.

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