Green development strategy for efficient quercetin- loaded whey protein complex: Focus on quercetin loading characteristics, component interactions, stability, antioxidant, and in vitro digestive properties
Abstract
This study aimed to develop a quercetin-loaded whey protein complex using pH-induced co-assembly for the intestinal-targeted delivery of quercetin. The investigation focused on quercetin loading capacity, formation mechanism, stability, antioxidant activity, and in vitro digestive properties of the complex. The results indicated that the stable complex was obtained at a quercetin-to-protein mass ratio of 1:20, exhibiting a high encapsulation efficiency (96.4 %) and loading capacity (4.6 %). Interaction studies revealed that quercetin binds to whey protein via hydrophobic interactions and hydrogen bonding, forming an irregular layered structure. Stability analysis demonstrated that the complex possesses high ionic and thermal stability. The antioxidant capacity of quercetin was significantly enhanced by complex encapsulation. In vitro digestion studies showed that the complex could pass through the gastrointestinal tract smoothly and effectively improve the bio-accessibility of quercetin. These findings provide a theoretical basis for the application of whey protein-based quercetin delivery systems in the functional food field.
Read the paper
Related studies
- Quercetin Influences Quorum Sensing in Food Borne Bacteria: In-Vitro and In-Silico Evidence
- Phenolic-protein interactions: insight from in-silico analyses – a review
- In Silico Discovery of Candidate Drugs against Covid-19
- Neuropharmacological Effects of Quercetin: A Literature-Based Review
- In vitro and in silico anti-dengue activity of compounds obtained from Psidium guajava through bioprospecting
- Effect of Quercetin Rich Onion Extracts on Bacterial Quorum Sensing
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.