Prospective Cohort Study on Patients With Tedizolid Prolonged Therapy for Orthopedic Device Infections
Abstract
Pilot study the aim of which is to obtain reliable data on the tolerance, compliance and efficacy of Tedizolid used as prolonged (≥ 6 weeks) monotherapy or in combination therapy for the treatment of patients with orthopedic device infections due to Gram positive cocci.
Conditions: Prosthetic Joint Infection.
Primary outcome: Bone marrow toxicity; Peripheral neuropathy; Metabolic acidosis; Serotoninergic syndrome; Retrobulbar optic nevritis.
Enrollment: 35 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 35 participants or records.
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