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Saliva and Dried Blood Spot Therapeutic Drug Monitoring for MDR-TB in Tanzania

ClinicalTrials.gov · COMPLETED, 2019

51 participants

Abstract

Dried blood spot and saliva samples are collected during multidrug resistant tuberculosis (MDR-TB) treatment to measure the drug concentration of levofloxacin. Feasibility of both analytical procedures in a high burdened setting is explored.

Conditions: MDR-TB.

Primary outcome: Drug exposure.

Enrollment: 51 participants.

How strong is the evidence?

Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 51 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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