Corticosteroid therapy and changes in chest radiogram in five patients with severe acute respiratory syndrome
Abstract
OBJECTIVE: To investigate the relationship between corticosteroid therapy and kinetic changes in chest X-ray in five patients with severe acute respiratory syndrome (SARS).
METHODS: With the identical underlying therapy (levofloxacin or ceftriaxone and macrolide), intravenous methylprednisolone was given at 80 mg twice a day in five patients, and its effect on the development of chest radiogram was observed.
RESULTS: Chest X-rays radiogram showed significant changes until peak stage (4-12 days) with the same doses of methylprednisolone, but it was dissolved consistently afterwards.
CONCLUSION: It is appeared that corticosteroid therapy has no marked effect on the development of chest radiogram in patients with SARS. It might indicate there is self-limited in course of SARS.
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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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