Gambaran Pemakaian Antibiotika Setelah Implementasi Pedoman Pemakaian Antibiotika di Bangsal Kenanga RSUD Arifin Achmad Provinsi Riau Periode Juni-Agustus 2016
Abstract
Implementation of antibiotic guideline as part of “Antibiotic Stewardship Programs (ASPs)”, can both optimize the treatment of infections and reduce adverse events associated with antibiotic use, antibiotic resistance and saving hospitals funds. This study describes quantitative and qualitative evaluation and cost of antibiotic use after implementation of antibiotic guideline in Kenanga ward Arifin Achmad General Hospital.This research was a descriptive prospective study. All inpatients given antibiotic in Kenanga ward from June – August 2016 were evaluated. The quantitative antibiotic use was calculated with DDD (daily define dose) meanwhile Gyssens method was used to calculate qualitative of antibiotic use. There were 137 patients fulfilled inclusion criteria. The most antibiotic used were ceftriaxone, ciprofloxacin, levofloxacin, meropenem and cefoperazone. There was increased consumption of quinolone class antibiotics. The highest DDD’s antibiotic was ceftriaxone (96.5). Qualitative measurement showed that rational antibiotic (Gyssens category 0) was 46%, irrational (Gyssens category I - IV) was 35 % and no indication of antibiotic use (Gyssens category V) was 19%. The total cost of antibiotics in this period were Rp 41,444,766.After antibiotic guideline implementation, we found that the most frequent antibiotic was ceftriaxone and irrational use of antibiotic was still high.
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