Antibiotic-Resistant Bacteria in Intensive Care Units in the Kingdom of Saudi Arabia: A Systematic Review
Abstract
Background: The emergence of bacterial pathogens and their associated resistance to antibiotic therapy is one of the most serious public health concerns threatening today’s society, including Saudi Arabia’s intensive care units (ICUs). Aim: This study used a systematic review to explore the antibiotic-resistant bacteria in the intensive care units (ICUs) in Saudi Arabia. Methods: The review adhered to the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 guidelines. The search was limited to studies published within 13 years between 2010 and 2023 through CINAHL, Web of Knowledge, PubMed, Science Direct, and Google Scholar. Results: Fifteen studies were reviewed: 12 were retrospective, 1 was comparative historical, 1 was descriptive epidemiologic and 1 was a surveillance study. Most frequently isolated antibiotic-resistant bacteria were Klebsiella pneumonia, Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, and Enterobacter. These pathogens were found resistant to various antibiotics including methicillin, tazobactam, cilastatin, meropenem, tigecycline, imipenem, meropenem, piperacillin, colistin, penicillin, ampicillin, oxacillin, vancomycin, carbapenems, amoxicillin, ceftriaxone, amikacin, gentamicin, clindamycin, azithromycin, levofloxacin, nitrofurantoin, trimethoprim, cefuroxime, ciprofloxacin, aztreonam, and cefotaxime. Conclusion: To eradicate future infection outbreaks of K. pneumonia, P. aeruginosa, A.…
How strong is the evidence?
Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.