Controlled clinical trials of moxifloxacin in old patients with community-acquired pneumonia
Abstract
OBJECTIVE To evaluate the efficiency and safety of moxifloxacin in old patients with community-acquired pneumonia(CAP).METHODS Aprospective design was conducted.80 old patients with CAP were randomly divided into trial group and control group.The 40 trial group members were treated with moxifloxacin.In the control group,40 patients were treated with levofloxacin and ceftriaxone sodium.Statistical difference was analyzedinterms effectiveness,side effects and the comparisons were made between the groups.RESULTS After treatment,the total cured rate for the trail group was 95%,while for the control group it was 77.5%;P0.05.The adverse drug reaction rates were evaluated in 80 patients,showing the rates were 7.5% and 10% respectively with no significant statistical differences(P0.05).CONCLUSION Moxifloxacin is effective and safe in the treatment of old patients with CAP.
Read the paper
Related studies
- Structural and topological analysis of thiosemicarbazone-based metal complexes: computational and experimental study of bacterial biofilm inhibition and antioxidant activity
- Toward better cures for Mycobacterium abscessus lung disease
- Challenges for global antibiotic regimen planning and establishing antimicrobial resistance targets: implications for the WHO Essential Medicines List and AWaRe antibiotic book dosing
- Design, Synthesis and In vitro Antitubercular Effect of New Chalcone Derivatives Coupled with 1,2,3‐Triazoles: A Computational Docking Techniques
- Upregulation of pmrA, pmrB, pmrC, phoQ, phoP, and arnT genes contributing to resistance to colistin in superbug Klebsiella pneumoniae isolates from human clinical samples in Tehran, Iran
- Whole-genome sequencing of clinical isolates of Citrobacter Europaeus in China carrying blaOXA−48 and blaNDM−1
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.