Modern concepts and biomarkers of blood stasis in cardio- and cerebrovascular diseases from the perspectives of Eastern and Western medicine: a scoping review protocol
Abstract
OBJECTIVE
The objective of this review is to provide a modern definition and identify potential biomarkers of blood stasis in cardio- and cerebrovascular diseases by mapping, comparing, and combining Eastern and Western concepts.
INTRODUCTION
Blood stasis is a pathological concept found in both Eastern and Western medical literature. In traditional East Asian medicine, blood stasis is a differential syndrome characterized by stagnant blood flow in various parts of the body. Similarly, in Western medicine, various diseases, especially cardio- and cerebrovascular diseases, are known to be accompanied by blood stasis. Numerous scientific studies on blood stasis have been conducted over the last decade, and there is a need to synthesize those results.
INCLUSION CRITERIA
We will use the keywords "blood stasis," "blood stagnation," "blood stagnant," and "blood congestion" in three electronic databases: PubMed, Cochrane CENTRAL, and Google Scholar. In addition, we will use the keywords JOURNAL/jbes/04.03/02174543-990000000-00011/inline-graphic1/v/2022-08-10T105117Z/r/image-jpeg and JOURNAL/jbes/04.03/02174543-990000000-00011/inline-graphic2/v/2022-08-10T105117Z/r/image-jpeg in four Korean electronic databases (ie, NDSL, OASIS, KISS, and DBpia). Peer-reviewed articles published from 2010 to the present that focus on blood stasis in cardio- and cerebrovascular diseases in human subjects according to the International Classification of Diseases 11th revision categories BA00-BE2Z,…
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