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The effect of lower limb rehabilitation robot on lower limb -motor function in stroke patients: a systematic review and meta-analysis

Qing-Hong Hao, Mi-Mi Qiu, Jun Wang, Yang Tu, Zhi-Hai Lv, Tianchi Zhu

Systematic Reviews, 2025

3,279 participants · 13 citations

Abstract

BACKGROUND: The assessment and enhancement of lower limb motor function in hemiplegic patients is of paramount importance. The emergence of lower limb rehabilitation robots offers a promising avenue for improving motor function in these patients, addressing the limitations associated with traditional rehabilitation therapies. However, a consensus regarding their clinical effectiveness remains elusive. Consequently, the objective of this study is to systematically review the rehabilitation efficacy of lower limb rehabilitation robots on motor function in post-stroke hemiplegic patients, thereby providing robust clinical evidence to support their promotion and utilization.

METHODS: Eight databases were examined between the start and April 2024. Patients with hemiplegia were included in randomized controlled trials to examine the effects of a lower limb rehabilitation robot on their motor function. Data extraction, risk of bias assessment, and study screening were carried out independently by two reviewers. Stata and Review Manager 5.3 were used for the meta-analysis. Sensitivity analysis was used to determine how reliable the findings were. To examine the origins of heterogeneity, meta-regression and subgroup analysis were employed.

RESULTS: This review comprised a total of 41 studies with 3279 participants. In one or more domains, the majority of the studies were rated as having a low or uncertain risk of bias. The study's findings demonstrated that the lower limb walking…

How strong is the evidence?

Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 3,279 participants or records.

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