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A Pragmatic Randomized Controlled Trial of Ambient Artificial Intelligence to Improve Health Practitioner Well-Being

M. Afshar, M. R. Baumann, F. Resnik, Josie Hintzke, A. Sullivan, G. Wills, Kayla Lemmon, Jason Dambach et al.

NEJM AI, 2025

44 citations

Abstract

BACKGROUND Electronic health record (EHR) documentation is a major contributor to work-related practitioner exhaustion and the interpersonal disengagement known as burnout. Generative artificial intelligence (AI) scribes that passively capture clinical conversations and draft visit notes may alleviate this burden, but evidence remains limited. METHODS A 24-week, stepped-wedge, individually randomized pragmatic trial was conducted across ambulatory clinics in two states. Sixty-six health care practitioners were randomly assigned to three 6-week sequences of ambient AI. The coprimary outcomes were professional fulfillment and work exhaustion/interpersonal disengagement from the Stanford Professional Fulfillment Index. Secondary measures included time spent on notes, work outside work (WoW), documentation quality with the Provider Documentation Summarization Quality Instrument 9 (PDSQI-9), and billing diagnostic codes reviewed by professional staff coders. Linear mixed models were used for intention-to-treat (ITT) analyses. RESULTS A total of 71,487 notes were authored, of which 27,092 (38%) were generated using ambient AI. Ambient AI use had a significant reduction in work exhaustion/interpersonal disengagement (−0.44 points; 95% confidence interval [CI], −0.62 to −0.25; P<0.001), and a nonsignificant increase in professional fulfillment (+0.14 points; 95% CI, 0.004 to 0.28; P=0.04) on a five-point Likert scale. Among secondary measures, time spent on notes decreased (−0.36…

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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