Zirconia-reinforced glass ionomer restorations in molar incisor hypomineralization: a randomized controlled clinical trial
Abstract
This study aimed to evaluate the effectiveness of zirconia-reinforced glass ionomer (ZrGI), in reducing pain and sensitivity, and to assess its clinical success in comparison to glass-hybrid glass ionomer (GhGI) in hypomineralized permanent first molars (HPFM) following the Atraumatic Restorative Treatment (ART) approach. This randomized controlled clinical trial included 7–10-year-old children. Eighty-eight HPFMs with evidence of caries, with or without hypersensitivity were included. These molars scored (2a), (2b), (4a), or (4b) according to the MIH Treatment Need Index (MIH-TNI). Selective caries removal was performed using the ART protocol. The test group received ZrGI (Zirconomer®) restorations, and the control group received GhGI (Equia Forte®) restorations. Pain and sensitivity were assessed pre-operatively, using the Visual Analogue Scale (VAS), then re-assessed post-operatively after 1 week and after 3,6,9, and 12 months (M). Clinical success was evaluated, starting from the 3-month visit, using the ART evaluation criteria. After 12M, the median pain scores for the ZrGI gp., (Q1-Q3; 0.00 – 0.00) and GhGI gp., (Q1-Q3; 0.00 – 0.00) showed no statistically significant difference, (p = 0.329). Median sensitivity scores for the ZrGI gp., (Q1-Q3; 0.00 – 5.00) and the GhGI gp., (Q1-Q3;0.00 – 3.50), also showed no statistically significant difference, (p = 0.344). No significant difference was found between the 12M success rate of ZrGI (86.4%) and GhGI (84.1%), (p = 0.765).…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.
Read the paper
Related studies
- Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials
- Tocilizumab in patients with severe COVID-19: a retrospective cohort study
- A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study
- Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study
- Are noise and air pollution related to the incidence of dementia? A cohort study in London, England
- Long COVID symptoms and duration in SARS-CoV-2 positive children — a nationwide cohort study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.