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Drug survival of IL‐23 and IL‐17 inhibitors versus other biologics for psoriasis: A British Association of Dermatologists Biologics and Immunomodulators Register cohort study

Leila Motedayen Aval, Z. Yiu, O. Alabas, C. Griffiths, N. Reynolds, P. Hampton, Catherine H. Smith, R. Warren

Journal of the European Academy of Dermatology and Venereology, 2025

31 citations

Abstract

Interleukin (IL)‐23p19 and IL‐17 inhibitors have demonstrated high efficacy for psoriasis in randomized controlled trials, though real‐world data, particularly for risankizumab (IL‐23p19 inhibitor) and brodalumab (IL‐17 receptor (IL‐17R) inhibitor), is limited.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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