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High Prevalence of Cold Intolerance in Rheumatoid Arthritis: A Case–Control Study

M. Soroush, Rojin Farzaneh, Elaheh Babapour, Amirreza Jabbaripour Sarmadian, Sami Rassouli, Golrokh Hassanzadeh Behrouz, Amirreza Naseri, M. Mahmoudi et al.

Clinical Case Reports, 2025

Abstract

Cold intolerance is more common in rheumatoid arthritis patients than control. Cold intolerance tends to develop after rheumatoid arthritis onset and is associated with longer disease duration, with pain and swelling being dominant features. Cold intolerance leads to a reduced quality of life in rheumatoid arthritis patients.

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