Beyond Catheter Presence: Risk Factors for Progression to Bloodstream Infection During the COVID-19 Era - A Matched Case-Control Study
Abstract
This matched case-control study evaluated 318 hospitalized patients with central venous catheters between 2018 and 2022 to identify risk factors for central line-associated bloodstream infection. Independent risk factors included immunosuppression, longer catheter dwell time, and prolonged hospitalization. Klebsiella pneumoniae predominated among isolates, and the pandemic period was associated with increased carbapenem and quinolone resistance, highlighting the need for sustained infection prevention and antimicrobial stewardship strategies.
How strong is the evidence?
Evidence Hub reads this as a case-control, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 318 participants or records.
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